Monday, April 22, 2013

?An accident waiting to happen? (Offthekuff)

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North Carolina man rolls 1st PBA 900 series

THE VILLAGES, Fla. (AP) ? A North Carolina man has rolled the first 900 series in Professional Bowlers Association history ? three straight perfect games.

Joe Scarborough, a 50-year-old self-employed electrical contractor from Charlotte, opened the first round of qualifying in the PBA50 Sun Bowl on Sunday with three games of 300, throwing 36 consecutive strikes.

Scarborough was competing in his second event in the renamed PBA Senior Tour. He said his previous high three-game series was an 838 and he had bowled 14 prior 300 games.

Scarborough was a PBA member from 1991-2001 and twice bowled in standard PBA Tour events. He rejoined when he turned 50 in October.

"I'm pretty surprised," Scarborough said. "I had the shot, I took my time and it worked out. To be honest, no, I wasn't nervous. I was pretending I was at home practicing, and I blocked out the crowd and focused on executing every shot."

Norm Duke had three consecutive 300s in a standard PBA Tour event in 1996, the PBA said Monday, but the performance didn't count as a 900 series because he ended one round with two perfect games and started the next round with the third.

Scarborough threw another strike to start his fourth game, but his streak ended at 37 when he left a split on his next shot. Three straight sub-200 games then knocked him out of the lead and into a tie for 12th place with 1,921 pins, 77 behind the leader, PBA Hall of Famer Mark Williams.

Source: http://news.yahoo.com/north-carolina-man-rolls-1st-pba-900-series-152240359--spt.html

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Intensity modulated radiotherapy reduces side effects in patients with early breast cancer

Apr. 21, 2013 ? Intensity modulated radiotherapy (IMRT) gives better results than standard radiotherapy in patients with early breast cancer, according to results from a randomised trial presented today (Sunday) to the 2nd Forum of the European Society for Radiotherapy and Oncology (ESTRO). IMRT is an advanced, high-precision form of radiotherapy that can deliver an even dose of radiation, thus reducing the cosmetic problems that can often occur after breast radiotherapy.

"We believe that this study, the largest prospective trial in the world to test breast IMRT against standard two-dimensional radiotherapy, will be practice-changing at an international level," said Dr Charlottes Coles, from Addenbrooke's Hospital Oncology Centre, Cambridge, UK. "Analysing the results five years after treatment, we saw significant benefits in patients who had received IMRT."

The researchers analysed the radiotherapy treatment plans of 1145 patients with early breast cancer who had previously had breast-conserving surgery. The plans were screened to see if they would produce an uneven radiation dose with standard two-dimensional radiotherapy (2DRT). A total of 71% of the plans fell into this category, and those patients were randomised between standard 2DRT and IMRT. The 29% of patients whose plans would not produce an uneven dose were treated with standard 2D RT, but still followed up within the trial.

One of the aims of external radiotherapy is to treat the target -- in this case the whole breast -- with an even dose distribution, i.e. within a range of 95% to 107% of the prescribed dose. Too low a dose can risk tumour recurrence, and too high a dose can cause undesirable side-effects such as skin changes.

"The problem with 2D breast radiotherapy is that the dose distribution is only recorded across the central part of the breast. Usually it meets the 95-107% constraints, but the shape of the breast changes, so if the same plan is looked at in 3D, then there may well be areas with overly high doses. By modulating the intensity of the radiation beam, IMRT can be used to correct for this and smooth out the dose," said Dr Coles.

The researchers set out to see whether the effect of using IMRT in those patients who would have received a dose greater than 107% to parts of their breast with 2DRT would translate into clinical benefit. IMRT planning uses results from scans to determine the dose intensity that will best treat the tumour, and therefore is more complex and time-consuming than 2DRT planning, so there was an important need to see a clear advantage to patients from the use of the procedure.

The only previous study looking at this was much smaller, and rather than picking out all patients with doses greater than 107% and randomising them, it only included women with larger breasts who are already known to be more likely to have regions of dose above the upper limit. "Our trial was more inclusive as all women were able to take part and we could quantify those who would receive an uneven dose," said Dr Coles.

"We saw that fewer patients in the IMRT group developed skin telangiectasia (dilated blood vessels near the surface of the skin), and the overall cosmetic effect in the breast was better," she said. Although there was no significant difference between the two groups in breast shrinkage, breast oedema, breast induration (hardening), and pigmentation changes, the benefits of using IMRT in these patients were clear.

The researchers intend to follow up their work by analysing the patients' questionnaires to see whether IMRT has an influence on quality of life. The trial has also contributed 1000 blood samples to the UK translational research study RAPPER (Radiogenomics: Assessment of Polymorphisms for Predicting the Effects of Radiotherapy), which aims to ultimately develop individualised radiotherapy plans based on the analysis of individual patients' genetics.

"Although IMRT is employed increasingly in breast cancer, its use is far from universal throughout the world. We hope that the evidence of benefit shown in our trial will encourage its greater use, resulting in improved patient access and, ultimately, improved outcomes for breast cancer patients," said Dr Coles.

President of ESTRO, Professor Vincenzo Valentini, a radiation oncologist at the Policlinico Universitario A. Gemelli, Rome, Italy, said: "This study not only shows a better outcome for the women treated with IMRT, but has an additional value in defining the selection criteria for providing treatment to those patients who will benefit from new frontline technologies. In the study design, the patients who could be treated satisfactorily by standard technology were not referred for IMRT, avoiding the use of a complex technique where it was not necessary. At a time when resources are limited, individualised medicine can help us offer new technology only to those patients who will have a tangible benefit from it."

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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/EFK4mMIN2Ko/130421074507.htm

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Humongous Chicago sinkhole swallows three cars, injures one driver

Following a severe rainstorm, a sinkhole opened up in Chicago's South Side, devouring three cars and sending one driver to the hospital. ?

By Eoin O'Carroll,?Staff / April 18, 2013

Officials survey a gaping sinkhole that opened up a residential street on Chicago's South Side after a cast iron water main dating back to 1915 broke during a massive rainstorm, Thursday in Chicago.

M. Spencer Green/AP

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A sinkhole opened up on a residential street on Chicago's South Side on Thursday morning, swallowing three cars and sending one person to the hospital.

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According to the Chicago Tribune, the sinkhole opened up at about 5 a.m. on Houston St. in?Chicago's South Deering neighborhood, where it quickly expanded from about 20 feet in diameter to about 40 feet. Two parked cars initially fell into the hole, and a third fell in as its driver was attempting to navigate around the hole and the ground below gave way. He?was taken to?Northwestern Memorial Hospital and is in "serious-to-critical" condition

According to the Associated Press, the sinkhole was preceded by a severe rainstorm that ruptured a water main in the neighborhood.?The AP quotes a spokesman from the city's water department, who speculated that the weight of the rain-soaked ground could have cracked the cast-iron pipe, which was laid in 1915. Water from the pipe would have then quickly eroded the soluble rock.

"The water will come out any way it can," the spokesman told the AP.?

Sinkholes are often caused by the underground erosion of salt beds or soluble sedimentary rocks, such as limestone or dolomite. Groundwater flows through these rocks, creating subterranean caverns that can suddenly collapse.

In recent years, sinkholes have appeared in Florida; California; Illinois; Washington, D.C.; Pennsylvania; Guangzhou, China;?Guatemala City;?Quebec;?Milwaukee; and Germany.

Source: http://rss.csmonitor.com/~r/feeds/science/~3/GuhKW1GXdP8/Humongous-Chicago-sinkhole-swallows-three-cars-injures-one-driver

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MOVIE REVIEW: Tom Cruise's 'Oblivion' is 'Moderately Clever ...

EDITOR'S NOTE: Oblivion is rated PG-13 and runs 126 minutes. It is now playing at North Point Market on North Point Parkway. For more theater information, show times and pricing, click the link above.

Tom Cruise leads a cast of well known actors in his latest thriller, out this weekend.

Here's what the critics are saying:

"The good news: Here's a lavish, serious science-fiction picture, one that on occasion transcends big-budget hit-making convention to glance against grandeur...Which brings us to Tom Cruise, the not-necessarily-good news. However engaging its end-times mysteries, Oblivion is still a Tom Cruise movie." Alan Scherstuhl, Village Voice. Full Review

"A moderately clever dystopian mindbender with a gratifying human pulse, despite some questionable narrative developments along the way." Justin Chang, Variety. Full Review

Movie information aggregated from?MovieFone.com

Do you plan on seeing this movie? Leave a review of the film with a comment below after you do.

Source: http://alpharetta.patch.com/articles/movie-review-tom-cruises-oblivion-is-amoderately-clever-mindbender

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Sunday, April 21, 2013

Modify Your Game Controller For Smaller Hands

If you have smaller-than-average hands, or you have kids who can't comfortably use a full-sized game controller, it's easy to modify the gamepad to better accommodate small thumbs.

This isn't a complete transformation, but it will at least make the control sticks easier to reach and manipulate. You can see the full process in the video above, but basically you'll use a Dremel to cut the "stalk" of the stick at an angle, rotate the top 180 degrees, then reattach it. You'll want the left stick facing out towards the left side of the controller, and vice versa for the right. The finished product probably won't be very comfortable if you can easily use an unmodified controller, but this would be great if you have an extra gamepad lying around for your kids.

How to Modify Your Xbox 360 Controller To Fit Your Really Tiny Hands | YouTube via WonderHowTo

Source: http://feeds.gawker.com/~r/lifehacker/full/~3/V5UMncERrNQ/modify-your-game-controller-for-smaller-hands-476391821

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